Table 2 Granuloma presentations in infected cattle.

From: Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle

Strain

Stage I

Stage II

Stage III

Stage IV

M. tuberculosis H37Rv (n = 4)

31

2

0

0

M. tuberculosis BTB1558 (n = 4)

20

5

0

0

M. bovis AF2122/97 (n = 4)

74

117

51

81

  1. One full histopathological section from each lymph node, tonsil and lung was stained with Haematoxylin and Eosin (H&E) and studied under light microscopy at x100 magnification to evaluate the total number of granulomas per development stage (I to IV). The granuloma development in both M. tuberculosis  strains was significantly different from M. bovis  AF2122/97, with granulomas only in the “early” development stages I and II while M. bovis infected animals presented granulomas in all developmental stages. P < 0.001 (X-sq for trend).
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