Figure 6
Combination of SEP and αPD-L1 on the effects of ERK1/2 phosphorylation in the spleen in B16-F10-bearing mice. The mouse spleens were harvested at the end of the experiment (day 16). The increase of P-ERK1/2 level in spleen was observed in three treatment groups compared with the control group (each treatment P < 0.05, respectively, n = 3). Combination of SEP and αPD-L1 significantly increases P-ERK1/2 level compared with SEP (P < 0.05, n = 3) or αPD-L1 (P < 0.05, n = 3). The results were presented as mean ± SEM. * P < 0.05 compared with control group. # P < 0.05, compared with SEP group. & P < 0.05, compared with αPD-L1 group.
