Table 1 Direct cytotoxicity of SEP and/or αPD-L1 antibody.

From: Combined SEP and anti-PD-L1 antibody produces a synergistic antitumor effect in B16-F10 melanoma-bearing mice

Gourp

Concentration (μg/mL)

48 h

72 h

96 h

SEP

1

0.92 ± 0.07

0.90 ± 0.03

0.94 ± 0.01

3

0.97 ± 0.03

0.92 ± 0.05

0.92 ± 0.04

10

0.95 ± 0.06

0.91 ± 0.06

0.93 ± 0.03

αPD-L1

1

0.98 ± 0.07

0.93 ± 0.09

0.95 ± 0.07

3

0.95 ± 0.10

0.97 ± 0.03

0.91 ± 0.03

10

0.93 ± 0.08

0.92 ± 0.06

0.93 ± 0.05

SEP + αPD-L1

1 + 1

0.90 ± 0.02

0.91 ± 0.03

0.91 ± 0.06

3 + 3

0.93 ± 0.04

0.93 ± 0.04

0.94 ± 0.01

10 + 10

0.91 ± 0.10

0.90 ± 0.10

0.93 ± 0.11

  1. Note: Mice melanoma B16F10 cells were inoculated on a 96 well plate. SEP and/or αPD-L1 antibody were administered at concentrations from 1 to 10 μg/ml. Growth rates were determined by MTT assay. Values are the mean ± SEM (n = 6).
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