Figure 3
From: The high concentration of progesterone is harmful for endometrial receptivity and decidualization
Effects of excess P on mouse decidualization and birth weight. (A) A representative photograph showing mouse day 8 uteri treated with oil or P (1,4 and 8 mg/mouse) daily from days 3 to 7. (B) The average weight of implantation sites on day 8 mice treated with oil or P (1,4 and 8 mg/mouse) daily from days 3 to 7. (C) A representative photo showing the deciduoma on day 8 pseudo-pregnant mice under artificial decidualization treated with oil or P (1,4 and 8 mg/mouse) daily from days 5 to 7. (D) The deciduoma weight on day 8 after pseudo-pregnant mice under artificial decidualization were treated with oil or P (1,4 and 8 mg/mouse) daily from days 5 to 7. (E) Effects of excess P on the expression of Dtprp, a marker for mouse in vitro decidualization. (F) Effects of excess P on the birth weight after pregnant mice were treated with oil or P (1,4 and 8 mg/mouse) daily from days 3 to 7, the weights of individual newborn fetus were counted. The real-time values are normalized to the RPL7 expression level and indicated as the mean ± SEM. n = 3. *P < 0.05.
