Figure 6 | Scientific Reports

Figure 6

From: Specific Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cells

Figure 6

Astrocyte differentiation but not neuronal differentiation is affected by blocking the MEK pathway. (a) Graph represents the percentage of astrocyte differentiation in the presence and in the absence of the MEK inhibitor (U0126 (20 μM)) and PtdEtn. (b) Graph represents the percentage of neuronal differentiation in the presence and in the absence of MEK inhibitor (U0126 (20 μM)) and PtdCho. (c) Western blot analysis was used to investigate the amount of p-ERK and ERK (control) in cells treated with the indicated phospholipids or control cells. The gels/blots displayed here are cropped, and without high-contrast (overexposure). The full-length gels and blots are included in a Supplementary Information file. (d) Graph represents the percentage of neuronal differentiation in the presence and in the absence of the Raf inhibitor (BAY-43-9006 (3.5 μM)) and PtdEtn. Values were obtained from three independent experiments. Data were presented as mean ± SEM *p < 0.05.

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