Table 2 Microelectrode measurements and repetitive nerve stimulation in Fgf18+/+ and FGF18−/− mice at E18.5.

From: Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters

 

Fgf18+/+

Fgf18−/−

p

MEPP amplitude (mV)

3.53 ± 0.33 (n = 16)

2.89 ± 0.70 (n = 18)

0.04

MEPP frequency (sec−1)

0.71 ± 1.08 (n = 16)

0.09 ± 0.09 (n = 18)

0.01

Fifth CMAP area (%)

120.5 ± 15.55 (n = 5)

58.4 ± 8.01 (n = 3)

0.0004

  1. Miniature endplate potentials (MEPPs) are recorded from five to six NMJs of the left diaphragm of each of three Fgf18+/+ and three Fgf18−/− mice at E18.5. Relative areas of the fifth and first compound muscle action potentials (CMAPs) at the 2-Hz stimulation of the sciatic nerve in five Fgf18+/+ and three Fgf18−/− are indicated. Mean and standard error of mean are indicated. Statistical significance (p) is calculated with the Student’s t-test.
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