Figure 8
MRI and micro-CT analysis of brain and skull in WT and Ach mice. (A) Representative WT and Ach mice brains of 3-week-old mice are shown in the sagittal and coronal orientations. The red, green and white arrows indicate anatomical differences between the two groups. (B) Summary of the brain volumes using MRI are shown for 3- and 6-week-old mice. (C) Representative WT and Ach skull bones from 3-week-old mice are shown in the transverse and sagittal orientations. (D) Summary of the skull bone volumes using micro-CT are shown for 3- and 6-week-old mice. (E) A fusion of the brain MRI and skull micro-CT data are shown for better multimodal visualization. The graphical data are represented as mean ± SEM (****p < 0.0001).
