Table 2 Summary of all between-group effects considered substantial in magnitude (see Supplementary Data Table 2 for a full list of all between-group statistical comparisons).
Measure | Comparison | Change between | Mean difference in change | Standardised effect size (ES) | Effect magnitude | Qualitative likelihood of true effect magnitude being substantial | ||
|---|---|---|---|---|---|---|---|---|
% difference | ±90% CL | ES ( d ) | ±90% CL | |||||
Maximal strength | ||||||||
1-RM leg press | HIT+RT vs. RT | PRE-POST | −7.4 | 8.7 | −0.40 | 0.40 | small | likely |
MICT+RT vs. RT | PRE-POST | −8.2 | 9.9 | −0.60 | 0.45 | moderate | likely | |
Markers of ribosome biogenesis | ||||||||
Total RNA | HIT+RT vs. RT | PRE-POST | 48 | 39 | 1.14 | 0.76 | moderate | very likely |
MICT+RT vs. RT | PRE-POST | 34 | 24 | 1.24 | 0.75 | large | very likely | |
45S pre-rRNA | HIT+RT vs. RT | PRE-POST | 58 | 76 | 0.71 | 0.71 | moderate | likely |
MICT+RT vs. RT | PRE-POST | 75 | 81 | 0.85 | 0.68 | moderate | likely | |
5.8S rRNA | HIT+RT vs. RT | PRE-POST | 125 | 109 | 1.27 | 0.73 | large | very likely |
MICT+RT vs. RT | PRE-POST | 120 | 111 | 0.99 | 0.61 | moderate | likely | |
5.8S rRNA (span) | HIT+RT vs. RT | PRE-POST | 112 | 116 | 1.40 | 0.97 | large | very likely |
28S rRNA | HIT+RT vs. RT | PRE-POST | 73 | 55 | 1.23 | 0.71 | large | very likely |
MICT+RT vs. RT | PRE-POST | 63 | 55 | 1.10 | 0.74 | moderate | likely | |
28S rRNA (span) | HIT+RT vs. RT | PRE-POST | 123 | 109 | 0.81 | 0.48 | moderate | likely |
Ribosome biogenesis-related signalling responses | ||||||||
p-TIF-1A Ser649 | HIT+RT vs. RT | POST-+3 h | −52 | 46 | −0.76 | 0.89 | moderate | likely |
MICT+RT vs. RT | POST-+3 h | −75 | 24 | −1.31 | 0.80 | large | very likely | |
p-UBF Ser388 | HIT+RT vs. RT | POST-+3 h | −49 | 17 | −0.92 | 0.45 | moderate | very likely |
MICT+RT vs. RT | POST-+3 h | −64 | 12 | −1.35 | 0.42 | large | most likely | |
HIT+RT vs. MICT+RT | POST-+3 h | −30 | 16 | −0.74 | 0.48 | moderate | likely | |
mRNA responses related to ribosome biogenesis | ||||||||
POLR1B mRNA | HIT+RT vs. RT | PRE-POST | 37 | 30 | 0.87 | 0.60 | moderate | likely |
POST-+3 h | 34 | 51 | 0.81 | 1.03 | moderate | likely | ||
AMPK/mTORC1-related signalling responses | ||||||||
p-ACC Ser79 | HIT+RT vs. RT | POST-+1 h | 99 | 100 | 0.65 | 0.46 | moderate | likely |
POST-+3 h | 169 | 168 | 0.94 | 0.56 | moderate | likely | ||
HIT+RT vs. MICT+RT | POST-+1 h | −58 | 23 | −0.82 | 0.49 | moderate | likely | |
p-AMPK Thr172 | MICT+RT vs. RT | POST-+3 h | −59 | 44 | −0.79 | 0.83 | moderate | likely |
p-p70S6K1 Thr389 | HIT+RT vs. RT | POST-+3 h | −47 | 50 | −0.86 | 1.13 | moderate | likely |
MICT+RT vs. RT | POST-+3 h | −50 | 46 | −0.88 | 1.05 | moderate | likely | |
p-rps6 Ser235/236 | MICT+RT vs. RT | POST-+3 h | −74 | 29 | −0.72 | 0.51 | moderate | likely |
Muscle fibre size | ||||||||
Type I fibre CSA | HIT+RT vs. RT | PRE-POST | −34 | 22 | −1.03 | 0.80 | moderate | likely |
