Figure 5 | Scientific Reports

Figure 5

From: 19F-perfluorocarbon-labeled human peripheral blood mononuclear cells can be detected in vivo using clinical MRI parameters in a therapeutic cell setting

Figure 5

MRI of human PBMC after flank administration in a mouse model. (a) Overlay produced from 19F and proton MR images following subcutaneous flank injection of 6 × 106 PBMC from participant 4. (b) On day 0, a 19F signal was observed in both the flank (blue arrow) and at the popliteal lymph node (yellow arrow). (c,d) Forty-eight hours after administration, the 19F signal was decreased but visible in the flank (c), but not detectable in the lymph node (d). The reference tube used to quantify the number of PBMC is marked with R in panel c. Scale bar = 5 mm.

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