Table 3 19F-PFC labeled PBMC detection by cellular MRI following injection in immunocompromised mice.

From: 19F-perfluorocarbon-labeled human peripheral blood mononuclear cells can be detected in vivo using clinical MRI parameters in a therapeutic cell setting

 

Participant 3

Participant 4

Participant 5

Injection Cell Number

Subcutaneous Flank

1 × 10 6

5.7 × 10 6

1 × 10 6

6 × 10 6

1 × 10 6

4 × 10 6

Day 0 Detection

Injection Sitea

No

Yes (1.13 × 106)

Yes (6 × 105)

Yesb (5.21 × 106)

No

Yes (1.11 × 106)

Day 2 Detection

Injection Site

No

Yes (7 × 105)

Yes (2.0 × 105)

Yes (4.11 × 106)

No

Yes (5.9 × 104)

  1. aDay 0 scan completed ~2 hours post injection.
  2. bDay 0 scan also detected 2 ×105 cells in the popliteal lymph node.
Back to article page