Table 2 Physiological parameters of WT vs. Cav1−/− mice upon water deprivation.
WT (n = 5) | Cav-1−/− (n = 6) | |
|---|---|---|
Urinary analysis (mean ± SD) | ||
Body weight, g | 28.5 ± 0.7 | 29.2 ± 0.7 |
Urinary volume, g/g body weight | 0.028 ± 0.003 | 0.041 ± 0.008 |
Na+ excretion, mmol/kg *18 h | 4.2 ± 1.1 | 5.9 ± 0.9 |
K+ excretion, mmol/kg *18 h | 7.2 ± 1.2 | 8.1 ± 1.0 |
Cl- excretion, mmol/kg *18 h | 6.9 ± 1.1 | 8.0 ± 1.4 |
Ca2+ excretion, mmol/kg *18 h | 0.07 ± 0.02 | 0.12 ± 0.03 |
Creatinine, mg/dl | 38.2 ± 1.7 | 30.3 ± 3.5 |
Creatinine, mg/g body weight | 0.011 ± 0.001 | 0.012 ± 0.002 |
Na+/creatinine ratio | 45.1 ± 2.6 | 58.2 ± 6.4 |
K+/creatinine ratio | 75.3 ± 6.6 | 81.2 ± 6.5 |
Cl-/creatinine ratio | 72.7 ± 5.1 | 79.3 ± 12.7 |
Ca2+/creatinine ratio | 0.72 ± 0.14 | 1.23 ± 0.24 |
Na+/K+ ratio | 0.63 ± 0.07 | 0.73 ± 0.07 |
