Table 1 Patients’ characteristics and clinicopathologic features (age ≤ 14).
From: Racial Differences in Four Leukemia Subtypes: Comprehensive Descriptive Epidemiology
ALL | AML | CML | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
HW | NHW | BL | API | HW | NHW | BL | API | HW | NHW | BL | API | |
Sample | 2066 | 2851 | 382 | 560 | 295 | 454 | 147 | 122 | 34 | 81 | 14 | 20 |
Gender | ||||||||||||
Male | 56 | 55.2 | 57.6 | 57.9 | 54.6 | 53.1 | 51.7 | 56.6 | 73.5 | 66.7 | 50 | 75 |
Female | 44 | 44.8 | 42.4 | 42.1 | 45.4 | 46.9 | 48.3 | 43.4 | 26.5 | 33.3 | 50 | 25 |
p-value | 0.52 | 0.77 | 0.43 | |||||||||
Age at diagnosis | ||||||||||||
≤4 | 53.2 | 56.6 | 44.5 | 57.7 | 46.4 | 46.9 | 49.7 | 49.2 | 50 | 43.2 | 21.4 | 50 |
5–9 | 27.7 | 27.2 | 31.7 | 29.3 | 21.4 | 20.7 | 19.7 | 19.7 | 5.9 | 18.5 | 21.4 | 20 |
10–14 | 19.1 | 16.2 | 23.8 | 13 | 32.2 | 32.4 | 30.6 | 31.1 | 44.1 | 38.3 | 57.1 | 30 |
p-value | <0.01 | 0.87 | 0.43 | |||||||||
Diagnosis era | ||||||||||||
1992–2001 | 51.2 | 58 | 54.7 | 51.8 | 51.5 | 59 | 46.3 | 54.9 | 44.1 | 49.4 | 64.3 | 55 |
2002–2011 | 48.8 | 42 | 45.3 | 48.2 | 48.5 | 41 | 53.7 | 45.1 | 55.9 | 50.6 | 35.7 | 45 |
p-value | <0.001 | 0.39 | 0.54 | |||||||||
Treatment | ||||||||||||
No radiation | 88.8 | 89.6 | 86.1 | 92 | 90.5 | 88.8 | 86.4 | 91 | 82.4 | 76.5 | 85.7 | 65 |
Radiation | 11 | 10 | 13.6 | 8 | 9.5 | 10.8 | 12.9 | 8.2 | 17.6 | 22.2 | 14.3 | 35 |
Unknown& | 0.1 | 0.4 | 0.3 | 0 | 0 | 0.4 | 0.7 | 0.8 | 1.2 | |||
p-value | 0.035 | 0.94 | <0.01 | |||||||||
Registry | ||||||||||||
West | 91.2 | 56 | 41.6 | 90 | 88.8 | 57.7 | 40.8 | 91 | 85.3 | 50.6 | 50 | 85 |
Northeast | 3.7 | 12.2 | 5.5 | 1.4 | 6.1 | 11 | 10.2 | 0.8 | 8.8 | 17.3 | ||
Midwest | 2.3 | 24.8 | 25.7 | 4.8 | 2 | 25.6 | 18.4 | 4.1 | 5.9 | 24.7 | 21.4 | 10 |
South | 2.8 | 7 | 27.2 | 3.8 | 3.1 | 5.7 | 30.6 | 4.1 | 7.4 | 28.6 | 5 | |
p-value | <0.01 | <0.01 | <0.01 | |||||||||
Cancer history | ||||||||||||
No | 98.6 | 98.4 | 99.5 | 98.8 | 96.6 | 95.6 | 94.6 | 91 | 97.1 | 95.1 | 92.9 | 100 |
Yes | 1.4 | 1.6 | 0.5 | 1.3 | 3.4 | 4.4 | 5.4 | 9 | 2.9 | 4.9 | 7.1 | |
p-value | 0.38 | 0.4 | 0.08 | |||||||||
Survival (months) | 79.5 ± 60.7 | 94.3 ± 62.8 | 82.8 ± 63.3 | 84.2 ± 61.4 | 51.7 ± 55 | 63.8 ± 62.1 | 49.1 ± 56.4 | 52.6 ± 56.1 | 47.7 ± 47 | 59 ± 55.4 | 80.9 ± 73 | 71.3 ± 71.3 |
p-value | <0.01 | <0.01 | 0.25 | |||||||||
Histology type | ||||||||||||
Precursor cell LL,NOS | 62.5 | 66.6 | 63.4 | 58.8 | ||||||||
Precursor B-cell LL | 30.8 | 27.5 | 27.2 | 33.2 | ||||||||
Precursor T-cell LL | 3.3 | 3 | 6.3 | 3 | ||||||||
Acute ML NOS | 43.7 | 52.9 | 56.5 | 45.9 | ||||||||
Acute PL | 11.5 | 8.8 | 5.4 | 10.7 | ||||||||
Acute MML | 11.9 | 8.8 | 6.8 | 9 | ||||||||
Chronic ML NOS | 64.7 | 53.1 | 71.4 | 55 | ||||||||
Chronic MGL | 14.7 | 11.1 | 21.4 | 15 | ||||||||
Chronic MML,NOS | 5.9 | 6.2 | ||||||||||
Others& | 3.4 | 2.9 | 3.1 | 5 | 32.9 | 29.5 | 31.3 | 34.4 | 14.7 | 29.6 | 7.1 | 30 |
p-value | <.001 | 0.09 | 0.015 | |||||||||