Table 2 Patients’ characteristics and clinicopathologic features (age > 14).
From: Racial Differences in Four Leukemia Subtypes: Comprehensive Descriptive Epidemiology
ALL | CLL | AML | CML | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HW | NHW | BL | API | HW | NHW | BL | API | HW | NHW | BL | API | HW | NHW | BL | API | |
Sample | 1438 | 2705 | 332 | 466 | 1285 | 24620 | 1835 | 718 | 2393 | 16565 | 1747 | 2224 | 1156 | 7874 | 974 | 864 |
Gender | ||||||||||||||||
Male | 58.9 | 57.5 | 53 | 55.6 | 57.1 | 59.5 | 57.8 | 62.3 | 53.4 | 54.7 | 49.1 | 51.7 | 58.7 | 58 | 56.9 | 61.7 |
Female | 41.1 | 42.5 | 47 | 44.4 | 42.9 | 40.5 | 42.2 | 37.7 | 46.6 | 45.3 | 50.9 | 48.3 | 41.3 | 42 | 43.1 | 38.3 |
p-value | 0.24 | 0.06 | <0.01 | 0.28 | ||||||||||||
Age at diagnosis | ||||||||||||||||
15–34 | 55.2 | 30.8 | 38.3 | 35.4 | 0.5 | 0.2 | 0.4 | 0.4 | 24.1 | 6.2 | 11 | 12.4 | 20.8 | 6 | 13.1 | 14.6 |
35–54 | 24.9 | 24.7 | 30.4 | 28.5 | 13.1 | 10.4 | 14.9 | 14.5 | 26.7 | 15.8 | 25.4 | 23.4 | 34.4 | 19.4 | 31.4 | 29.7 |
≥55 | 19.9 | 44.5 | 31.3 | 36.1 | 86.4 | 89.3 | 84.6 | 85.1 | 49.1 | 78 | 63.6 | 64.2 | 44.8 | 74.7 | 55.4 | 55.7 |
p-value | <0.01 | <0.01 | <0.01 | <0.01 | ||||||||||||
Diagnosis era | ||||||||||||||||
1992–2001 | 43.3 | 54.1 | 46.7 | 46.4 | 45.4 | 50.4 | 50.9 | 41.2 | 47.3 | 54.5 | 50.1 | 47.7 | 51.4 | 55.3 | 52.5 | 51.3 |
2002–2011 | 56.7 | 45.9 | 53.3 | 53.6 | 54.6 | 49.6 | 49.1 | 58.8 | 52.7 | 45.5 | 49.9 | 52.3 | 48.6 | 44.7 | 47.5 | 48.7 |
p-value | <0.01 | <0.01 | <0.01 | 0.012 | ||||||||||||
Treatment | ||||||||||||||||
No radiation | 75.8 | 77.4 | 80.1 | 75.1 | 96.9 | 97.2 | 97.5 | 94.6 | 92.1 | 94.2 | 95.1 | 92.8 | 92.8 | 94.8 | 96 | 92.6 |
Radiation | 22.7 | 20.8 | 17.8 | 22.1 | 0.9 | 0.7 | 0.8 | 0.6 | 6.1 | 4 | 3.3 | 5.6 | 5.2 | 3.1 | 2.5 | 4.4 |
Unknown** | 1.5 | 1.7 | 2.1 | 2.8 | 2.3 | 2.2 | 1.6 | 4.9 | 1.7 | 1.9 | 1.6 | 1.6 | 2 | 2.1 | 1.5 | 3 |
p-value | 0.3 | 0.7 | <0.01 | <0.01 | ||||||||||||
Registry | ||||||||||||||||
West | 91.8 | 55 | 45.5 | 89.9 | 90 | 57.1 | 44 | 95.1 | 88.3 | 54.9 | 44.6 | 94.1 | 90 | 56 | 41.5 | 92.9 |
Northeast | 4 | 12.7 | 6.9 | 3.6 | 4.6 | 11.3 | 6.3 | 0.8 | 5.8 | 12 | 7.4 | 1.3 | 4.9 | 10.7 | 6.2 | 1.5 |
Midwest | 1.6 | 25.5 | 21.1 | 3 | 3.4 | 27.4 | 32.6 | 3.3 | 3.3 | 27.2 | 29.1 | 2.3 | 2.8 | 28.6 | 30.8 | 3.6 |
South | 2.6 | 6.8 | 26.5 | 3.4 | 2 | 4.3 | 17.2 | 0.7 | 2.7 | 5.9 | 18.9 | 2.3 | 2.3 | 4.7 | 21.6 | 2 |
p-value | <0.01 | <0.01 | <0.01 | <0.01 | ||||||||||||
Cancer history | ||||||||||||||||
No | 92.7 | 84.6 | 87.7 | 89.9 | 75.8 | 69.3 | 68.9 | 74.9 | 85.5 | 75 | 76.9 | 83.3 | 88.4 | 76.7 | 80.4 | 83.4 |
Yes | 7.3 | 15.4 | 12.3 | 10.1 | 24.2 | 30.7 | 31.1 | 25.1 | 14.5 | 25 | 23.1 | 16.7 | 11.6 | 23.3 | 19.6 | 16.6 |
p-value | <0.01 | <0.01 | <0.01 | <0.01 | ||||||||||||
Survival (months) | 34 ± 43.8 | 35.6 ± 50.5 | 24.3 ± 35.1 | 36.7 ± 49.5 | 53.1 ± 48.3 | 59.3 ± 50.4 | 50.6 ± 44.7 | 55.6 ± 51.2 | 25.6 ± 42.7 | 17.5 ± 36.2 | 18.7 ± 37 | 22.3 ± 40.9 | 49.2 ± 49.9 | 40.6 ± 46.3 | 42.8 ± 45.9 | 47.9 ± 49.9 |
p-value | <0.01 | <0.01 | <0.01 | <0.01 | ||||||||||||
Histology type | ||||||||||||||||
Precursor cell LL,NOS | 53.5 | 64.9 | 61.7 | 58.8 | ||||||||||||
Precursor B-cell LL | 39.4 | 24.9 | 23.8 | 28.1 | ||||||||||||
Precursor T-cell LL | 3 | 3.6 | 7.8 | 7.7 | ||||||||||||
Acute ML NOS | 51.5 | 60.7 | 61.5 | 56.6 | ||||||||||||
Acute PL | 14.7 | 6 | 8.3 | 7.5 | ||||||||||||
Acute MML | 10.4 | 10.4 | 9.9 | 9.5 | ||||||||||||
Chronic ML NOS | 72.2 | 63.7 | 73.7 | 67.1 | ||||||||||||
Chronic MGL | 13.2 | 7.7 | 10.8 | 11.6 | ||||||||||||
Chronic MML,NOS | 14.4 | 28.3 | 15.3 | 20.5 | ||||||||||||
Others& | 4.2 | 6.6 | 6.6 | 5.4 | 23.5 | 22.8 | 20.3 | 26.4 | 0.2 | 0.3 | 0.2 | 0.8 | ||||
p-value | <0.01 | <0.01 | <0.01 | |||||||||||||
