Figure 6

Simulating SMA constriction cascade following pericyte constriction. Percentage changes in: 1) unconstricted and 2) constricted capillaries with uni-directional SMA propagation for (a) pressure, (b) flow, (c) velocity, (d) haematocrit (H D ) and (e) vessel PO2. (f) A plot of mean change in capillary PO2 against capillary order, as a result of local SMA constriction. Error bars represent standard deviation and, consequently, the redistribution of O2 through the cortical network.