Table 1 Characteristics of the Study Sample.

From: Placental Morphology Is Associated with Maternal Depressive Symptoms during Pregnancy and Toddler Psychiatric Problems

Maternal Characteristics

Data Available(N)

Mean(SDa)/N(%)

Age at Delivery (years)

88

31.5 (4.9)

Education, Tertiary

88

57 (64.8%)

Pre-Pregnancy Body Mass Index (kg/m2)

88

24.0 (4.2)

Any Diabetic or Hypertensive Disorder in Pregnancy (type 1 or gestational diabetes, chronic or gestational hypertension, pre-eclampsia), Yes

88

15 (17.0%)

History of Physician-Diagnosed Mental Disorders Before Pregnancy, Yes

80

13 (16.3%)

Depressive Symptoms

   Trimester-Weighted Mean Score of Center for Epidemiological Studies

86

10.3 (6.0)

Depression Scale Depressive Symptoms during Pregnancy

   Trimester-Weighted Mean Score of Center for Epidemiological Studies

86

14 (16.3%)

Depression Scale Depressive Symptoms during Pregnancy ≥ 16

   1st Pregnancy Trimester Center for Epidemiological Studies Depression

81

10.2 (6.7)

Scale Depressive Symptom Score

   Mean of 2nd Pregnancy Trimester Center for Epidemiological Studies

86

10.4 (6.5)

Depression Scale Depressive Symptom Scores

   Mean of 3rd Pregnancy Trimester Center for Epidemiological Studies

86

10.3 (6.6)

Depression Scale Depressive Symptom Scores

   Number of Pregnancy Trimesters with Center for Epidemiological Studies

81

 

     0

 

53 (65.4%)

     1

 

16 (19.8%)

     2–3

 

12 (14.8%)

Beck Depression Inventory-II Score Concurrently to Rating the Child

60

5.9 (5.5)

Placental Morphology

  

Volume of SMAb-Positive Villi per Placenta (ml)

88

95.1 (50.9)

Volume of Capillaries per SMA-Positive Villi per Placenta (ml)

88

56.0 (35.6)

Volume of SMAb-Negative Villi per Placenta (ml)

88

182.7 (63.9)

Volume of Capillaries per SMAb-Negative Villi per Placenta (ml)

88

157.5 (51.8)

Ratio of the Distribution of SMAb-Positive Villi to SMA-Negative Villi (%)

88

63.7 (56.8)

Villous Barrier Thickness of SMAb-Positive Villi (µm)

88

7.5 (1.7)

Standard Deviation of Villous Barrier Thickness of SMAb-Positive Villi (Variability in Thickness) (µm)

88

6.3 (2.3)

Villous Barrier Thickness of SMAb-Negative Villi (µm)

88

11.9 (4.6)

Standard Deviation of Villous Barrier Thickness of SMAb-Negative Villi (µm)

88

10.2 (5.5)

Placental Weight (grams)

88

589.7 (107.4)

Toddler Characteristics

  

Gestation Length (weeks)

88

40.3 (1.0)

Sex

88

 

       Boys

 

41 (46.6%)

       Girls

 

47 (53.4%)

Age at Follow-up (months)

60

25.5 (2.9)

Child Behavior Checklist/1½-5 Psychiatric Problems

  

Total Problems

60

46.8 (9.2)

Internalizing Problems

60

45.4 (8.5)

Externalizing Problems

60

48.6 (9.4)

  1. aSMA = γ-smooth muscle actin. bSD = standard deviation.