Table 1 Characteristics of the subjects from the Mount Sinaï Hospital cohort stratified by CDR scores (mean ± sem).

From: Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer’s disease at various cognitive stages

CDR

N

PMI (min)

AOD (years)

Gender (ratio f/m)

0

38

749.3 ± 11.7

78.4 ± 0.3

27 f/11 m (2.5)

0.5

21

521.9 ± 19.6

81.4 ± 0.5

9 f/12 m (0.8)

1

18

423.7 ± 22.3

85.7 ± 0.5

12 f/6 m (2)

2

14

485.1 ± 25.3

89.5 ± 0.5

11 f/3 m (3.7)

3

38

426.0 ± 8.0

88.2 ± 0.2

31 f/7 m (4.4)

4

21

351.5 ± 15.9

87.2 ± 0.4

13 f/8 m (1.6)

5

21

346.9 ± 14.9

87.8 ± 0.4

17 f/4 m (4.2)

  1. Abbreviations in Table: CDR: clinical dementia rating; N, size of the sample; PMI(min): post-mortem interval in minutes; AOD: age of death; f/m: females/males. One hundred seventy-one brain samples out of the 182 individuals were used and are presented  above.