Table 2 Haplogroup frequencies in 272 individuals with chronic HBV infection, 278 spontaneously recovered subjects and 310 healthy controls.
Haplogroupa | CHB vs. HC | CHB vs. SR | SR vs. HC | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CHB | HC | P valueb | OR (95% CI) | CHB | SR | P valueb | OR (95% CI) | SR | HC | P valueb | OR (95% CI) | |||
M* | 22 | 27 | 0.95 | 0.98 (0.48–2.00) | 22 | 23 | 0.86 | 0.93 (0.42–2.08) | 23 | 27 | 0.68 | 1.18 (0.55–2.52) | ||
M7 | 18 | 26 | 0.81 | 0.91 (0.44–1.91) | 18 | 26 | 0.18 | 0.57 (0.25–1.29) | 26 | 26 | 0.28 | 1.52 (0.71–3.26) | ||
M8 | 24 | 35 | 0.72 | 0.88 (0.45–1.74) | 24 | 28 | 0.43 | 0.74 (0.34–1.59) | 28 | 35 | 0.96 | 1.02 (0.50–2.10) | ||
D | 46 | 38 | 0.15 | 1.57 (0.85–2.89) | 46 | 42 | 0.87 | 1.06 (0.54–2.08) | 42 | 38 | 0.12 | 1.72 (0.87–3.41) | ||
D4 | 19 | 26 | 0.74 | 0.88 (0.41–1.87) | 19 | 19 | 0.86 | 0.92 (0.39–2.19) | 19 | 26 | 0.82 | 1.10 (0.49–2.49) | ||
D5 | 22 | 10 | 0.017 | 2.87 (1.21–6.81) | 22 | 9 | 0.049 | 2.90 (1.01–8.35) | 9 | 10 | 0.59 | 1.36 (0.44–4.19) | ||
A | 19 | 32 | 0.36 | 0.71 (0.35–1.47) | 19 | 21 | 0.63 | 0.82 (0.35–1.88) | 21 | 32 | 0.77 | 1.12 (0.52–2.40) | ||
R9 | 53 | 51 | 0.55 | 1.19 (0.67–2.14) | 53 | 64 | 0.54 | 0.82 (0.43–1.56) | 64 | 51 | 0.10 | 1.68 (0.90–3.13) | ||
F | 46 | 47 | 0.76 | 1.10 (0.60–2.01) | 46 | 51 | 0.71 | 0.88 (0.45–1.72) | 51 | 47 | 0.31 | 1.40 (0.74–2.66) | ||
F1 | 30 | 27 | 0.60 | 1.20 (0.60–2.41) | 30 | 38 | 0.46 | 0.76 (0.36–1.59) | 38 | 27 | 0.14 | 1.72 (0.84–3.53) | ||
B | 46 | 53 | 0.78 | 1.09 (0.61–1.96) | 46 | 42 | 0.91 | 0.96 (0.49–1.90) | 42 | 53 | 0.59 | 1.20 (0.63–2.29) | ||
B4 | 24 | 29 | 0.90 | 1.04 (0.52–2.10) | 24 | 23 | 0.65 | 0.83 (0.38–1.84) | 23 | 29 | 0.42 | 1.36 (0.64–2.90) | ||
B5 | 17 | 19 | 0.71 | 1.16 (0.53–2.54) | 17 | 16 | 0.71 | 1.19 (0.48–2.92) | 16 | 19 | 0.99 | 0.99 (0.41–2.39) | ||
others | 44 | 48 | — | — | 44 | 32 | — | — | 32 | 48 | — | — | ||
