Figure 10
From: Salient type 1 interleukin 1 receptor expression in peripheral non-immune cells

IL-1 induces c-fos expression in the IL-1R1-expressing FRCs in the spleen. Immunofluorescence labeling of RFP and c-fos in the spleen sections from IL-1R1GR/GR mice 2 hrs after intravenous IL-1β or saline injections. Arrow heads showed RFP+ and c-fos+ double labeled cells. Scale bar, 50 µm.