Table 1 Baseline characteristics of patients of hepatocellular carcinoma undergoing radiofrequency ablation (RFA).

From: Prognostic Performance of Ten Liver Function Models in Patients with Hepatocellular Carcinoma Undergoing Radiofrequency Ablation

Variables

Patients (n = 499)

Age (years, median [interquartile range])

67 [58–76]

Male, n (%)

326 (65)

Etiologies of liver disease

 HBV, n (%)

183 (37)

 HCV, n (%)

160 (32)

 HBV + HCV, n (%)

19 (4)

 Alcohol, n (%)

81 (16)

 Others, n (%)

75 (15)

aDiabetes mellitus, n (%)

143 (29)

Performance status (0/1/2-3), n (%)

370/76/53 (74/15/11)

Ascites, n (%)

69 (14)

Alpha-fetoprotein(ng/ml, median, [interquartile range])

18.24 [6.93–67.67]

Laboratory values (mean ± SD)

 Alanine aminotransferase (IU/L)

64.47 ± 55.04

 Aspartate aminotransferase (IU/L)

64.46 ± 52.88

 aAlkaline phosphatase (IU/L)

107.97 ± 78.85

 Albumin (g/dl)

3.75 ± 0.6

 Total bilirubin (mg/dl)

1.08 ± 1.06

 Creatinine (mg/dl)

1.184 ± 1.154

 Platelets (1,000/μL)

125.54 ± 62.13

 INR of prothrombin time

1.09 ± 0.14

Non-invasive liver function models

 ALBI grade (1/2/3), n (%)

209/261/29 (42/52/6)

 APRI grade (1/2/3), n (%)

122/205/172(24/41/35)

 CTP classification (A/B/C), n (%)

413/76/10 (83/15/2)

 CDS grade (1/2/3), n (%)

78/320/101 (16/64/20)

 FIB-4 grade (1/2/3), n (%)

37/138/324 (7/28/65)

 GUCI grade (1/2/3), n (%)

119/199/181 (24/30/46)

 Lok index grade (1/2/3), n (%)

204/196/99 (41/39/20)

 MELD score (1/2/3), n (%)

217/197/85 (43/40/17)

 PALBI grade (1/2/3), n (%)

273/157/69 (55/31/14)

 King’s score (1/2/3), n (%)

31/112/356 (6/22/72)

Tumor nodules (1/2/ ≥ 3), n (%)

384/79/36 (77/16/7)

Maximal tumor diameter (≤2/2-3/>3 cm), n (%)

206/172/121 (41/35/24)

TTV (ml, median, [interquartile range])

7.24 [2.57–16.25]

  1. ALBI, Albumin-bilirubin; APRI, Aspartate transaminase-to-Platelet ratio;
  2. CDS, Cirrhosis discriminant index; CTP, Child-Turcotte-Pugh score; FIB-4, Fibrosis-4 score; HBV, hepatitis B virus; HCV, hepatitis C virus; MELD, Model for End-stage liver disease; GUCI, Göteborg University Cirrhosis Index; PALBI, platelet-albumin-bilirubin; TTV, total tumor volume; SD, standard deviation;
  3. aMissing of data of DM and alkaline phosphatase were 3 (0.6%) and 28 (5.6%) patients, respectively.