Figure 2 | Scientific Reports

Figure 2

From: Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells

Figure 2

Procedure for calculating the area of methylation. (A–C) Illustration for transforming the methylation level data into a function. (A) Example of observed methylation levels (points) and methylation regions (segments below). (B) Fitted Gaussian functions (black curves) for each methylation levels. (C) By summing up these functions, we obtained a methylation function.

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