Figure 3
From: Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis
JQ1 diminished radiation-induced expressions of fibrosis markers. (A) Representative western blot pictures of BRD4, c-MYC, Collagen I, TGF-β, p-NFκB p65, NFκB p65, p-Smad2 and p-Smad3 in right lung tissues. Three samples from three different rats in each group were analyzed at 20 weeks postirradiation. GAPDH was used as a loading control. (B) Densitometric evaluation of protein bands normalized for GAPDH. Data were shown as the mean ± SD. *P < 0.05 vs. Radiation group, **P < 0.01 vs. Radiation group.
