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Figure 2

From: Cerebral Perfusion Insufficiency and Relationships with Cognitive Deficits in Alzheimer’s Disease: A Multiparametric Neuroimaging Study

Figure 2

Voxel-wise statistical analysis between patients with Alzheimer’s disease (AD) and controls. Areas of (A,D) atrophy; (B,E) decreased perfusion index (PI); and (C,F) decreased relative cerebral blood flow (rCBF) in the patients. Figure A–C: rendered onto 3-dimensional brain images with color intensity representing the depth from the brain surface. Figure D–F are representative slices with a color bar indicating the t-value scale. The overlapping areas between lower PI and atrophy in AD are shown in Fig. 1G. The overlapping areas between lower PI, rCBF and atrophy in AD are shown in Figure H. All images were statistically thresholded at p < 0.05, and a false discovery rate correction for multiple comparison, cluster > 200. SPECT = single-photon emission computed tomography; ASL = arterial spin labeling; PCC = posterior cingulate cortex.

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