Table 1 Evolutionary conservation of C. elegans SUMO targets with other species.

From: Comprehensive list of SUMO targets in Caenorhabditis elegans and its implication for evolutionary conservation of SUMO signaling

Species

Proteome

Homologues in C. elegans proteome

Homologues in C. elegans SUMO targets

Enrichment p-value

C. elegans

26723

   

H. sapiens

72874

6010

570

>2.2 × 10−16

M. musculus

50311

5977

580

>2.2 × 10−16

X. laevis

16378

4939

503

>2.2 × 10−16

D. melanogaster

21977

5066

529

>2.2 × 10−16

A. thaliana

31392

2993

393

>2.2 × 10−16

S. cerevisiae

6838

1886

275

>2.2 × 10−16

  1. C. elegans proteome and SUMO targets from C. elegans were compared to whole proteomes and to orthologues of C. elegans proteins in other species. Only strict homologues with BLASTP e-value smaller than 1 × 10−10 and over 80% of residues in both sequences included in the BLASTP alignment, were included in the comparison.