Figure 6
Effect of cathelicidin-OA1 on the repair rate of HSF cell wounds (scratches). (A) Cathelicidin-OA1 (10 nM) illustrated obvious HSF cell wound-healing activity. (B) Cathelicidin-OA1 (10 nM) illustrated HSF cell wound-healing activity when proliferation was inhibited by mitomycin C. (C) Cathelicidin-OA1 illustrated time- and dose-dependent HSF cell wound-healing activity. (D) Cathelicidin-OA1 illustrated time- and dose-dependent HSF cell wound-healing activity when proliferation was inhibited by mitomycin C. (E) At 10 pM to 10 nM, cathelicidin-OA1 showed no effect on the proliferation of HSF cells. ‘Vehicle’ is the negative control; *P < 0.05 and **P < 0. 01 indicated significantly different from the vehicle (Student’s t-test). Data are mean values of three independent experiments performed in triplicate.
