Table 3 Baseline variable concentrations and univariate logistic regression models for prediction of ongoing pregnancy at day 45 post-LH surge where P < 0.15.

From: Pre-conception maternal erythrocyte saturated to unsaturated fatty acid ratio predicts pregnancy after natural cycle frozen embryo transfer

Variable

Pregnant (n = 36)

Non-pregnant (n = 107)

Odds Ratio

Confidence Interval

P

C-statistic

Plasma metabolic and inflammatory markers

Triglyceride* (mmol/L)

1.01 (1.47)

0.90 (1.48)

2.15

(0.82, 5.63)

0.12

0.58

IL-6* (pg/mL)

1.14 (2.01)

0.90 (1.76)

1.86

(0.93, 3.72)

0.079

0.61

Erythrocyte fatty acids and summary measures

14:0 (nmol/mL)

12.8 (7.06)

9.60 (6.35)

1.07

1.00, 1.15

0.040

0.67

17:0 (nmol/mL)

6.94 (3.06)

5.72 (2.04)

1.21

1.00, 1.45

0.045

0.60

18:1 n-7 (nmol/mL)

6.31 (8.89)

10.64 (10.98)

0.96

0.92, 1.00

0.065

0.63

20:1 n-9 (nmol/mL)

4.24 (1.06)

4.94 (1.35)

0.61

0.41, 0.92

0.019

0.65

24:1 n-9 (nmol/mL)

64.5 (9.8)

70.2 (12.6)

0.96

0.92, 1.00

0.036

0.65

20:2 n-6 (nmol/mL)

0.66 (1.24)

1.30 (1.77)

0.76

0.55, 1.03

0.078

0.59

22:4 n-6 (nmol/mL)

38.5 (6.7)

43.1 (10.3)

0.94

0.89, 1.00

0.032

0.64

18:3 n-3 (nmol/mL)

3.93 (2.08)

2.95 (2.22)

1.24

1.00, 1.54

0.051

0.63

% Total n-6

27.8 (1.27)

28.4 (1.3)

0.67

0.46, 0.98

0.039

0.62

Unsaturated Index

150.1 (4.1)

151.5 (4.0)

0.92

0.82, 1.03

0.14

0.57

Average chain length† (0.05 units)

18.66 (0.05)

18.69 (0.06)

0.63

0.42, 0.95

0.027

0.66

Saturated/unsaturated ratio† (0.05 units)

0.78 (0.02)

0.76 (0.02)

7.19

2.33, 22.17

0.00059

0.75

Plasma fatty acids and summary measures

14:0 (nmol/mL)

118 (51)

98.3 (45.8)

1.01

1.00, 1.02

0.079

0.62

17:0 (nmol/mL)

30.0 (10.1)

25.6 (9.8)

1.05

1.00, 1.10

0.059

0.61

18:0 (nmol/mL)

618 (117)

577 (98)

1.00

1.00, 1.01

0.11

0.60

14:1 n-7 (nmol/mL)

41.7 (35.1)

29.6 (29.1)

1.01

1.00, 1.03

0.10

0.59

24:1 n-9 (nmol/mL)

88.5 (10.4)

94.3 (15.9)

0.97

0.94, 1.00

0.072

0.62

Saturated/unsaturated ratio† (0.05 units)

0.52 (0.05)

0.49 (0.04)

2.12

1.20, 3.76

0.010

0.66

% Total n-6

37.4 (3.09)

38.5 (3.4)

0.90

0.79, 1.04

0.15

0.60

Average chain length† (0.05 units)

17.80 (0.08)

17.84 (0.09)

0.75

0.57, 1.00

0.047

0.65

  1. Continuous variables are presented as mean (standard deviation) or * geometric means (standard deviation). Odds ratios are for a 1 unit increase in a variable apart from†. IL-6 = interleukin 6. IL-6 data was missing for n = 1 pregnant and n = 50 non-pregnant participants. Plasma triglyceride and plasma and erythrocyte fatty acid data was missing for n = 1 non-pregnant participant.
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