Table 4 Multivariable logistic regression models for predicting pregnancy success at 45 days post-LH surge.

From: Pre-conception maternal erythrocyte saturated to unsaturated fatty acid ratio predicts pregnancy after natural cycle frozen embryo transfer

Visit/Covariate

Multivariable

Odds Ratio (95% confidence interval)

P-value

C-statistic (Area Under Curve)

Baseline (mean of 3.4 days prior to LH surge)

Erythrocyte saturated/unsaturated fatty acid ratio (0.05 units)

7.19 (2.33, 22.17)

0.0006

0.75

Day of FET (mean of 2.8 days post-LH surge)

Erythrocyte saturated/unsaturated fatty acid ratio (0.05 units)

7.11 (2.05, 24.71)

0.002

0.84

Erythrocyte fatty acid average chain length (0.05 units)

0.58 (0.37, 0.92)

0.020

Log [triglyceride (mmol/L)]

4.23 (1.05, 16.95)

0.042

  1. Covariates to enter the stepwise logistic regression were initially selected using baseline, or day of FET (mean 2.8 days post-LH surge) stepwise logistic regression models run for all covariates (plasma and erythrocyte metabolic, inflammatory and fatty acid markers) P-to-enter and P-to-stay < 0.15). Variables included were baseline or day of FET triglyceride, IL-6 and insulin; erythrocyte 18:3 n-3, 20:1 n-9, 24:1 n-9, saturated/unsaturated fatty acid ratio and average chain length; and plasma 17:0, 24:1 n-9 and saturated/unsaturated fatty acid ratio. The final multivariable model is a stepwise model with P-to-enter and P-to-stay < 0.05. Data shown are the odds ratio (for the given unit of change), and the 95% confidence interval, with the associated Chi square score, P-value, and the C-statistic (for the Area under the Curve). FET = frozen embryo transfer.
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