Figure 7
From: High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation
Synthetic HDL retain the anti-oxidant effect of plasma-derived HDL. Panel a, synthetic HDL particle formation and size was verified by native GGE. LNCaP (Panel b) and PC-3 cells (Panel c) were stimulated with 0.5 mM H2O2 for 1 h. sHDL or apoA-I were tested at 0.5 mg/ml as a pre-treatment of 1 h or as co-incubation with H2O2 (co-inc). ROS production was evaluated by fluorescence. Data are expressed as relative fluorescent units (RFU) normalized by the protein concentration of total cell lysate, mean ± SD, n = 4. *P < 0.05 vs control, #P < 0.05 vs H2O2-stimulated cells.
