Table 6 Cox proportional hazard regression models for time to recurrence (TTR), cancer-specific survival (CSS), and overall survival (OS) according to normocytic anemia and clinicopathological characteristics.

From: Preoperative anemia in colorectal cancer: relationships with tumor characteristics, systemic inflammation, and survival

 

TTR

CSS

OS

HR

95% CI

p value

HR

95% CI

p value

HR

95% CI

p value

Tumor invasion (T1-T2 vs. T3-T4)

1.92

0.94–3.91

0.073

1.26

0.65–2.44

0.495

1.10

0.67–1.80

0.720

Nodal metastases (N0 vs. N1-N2)

5.25

2.89–9.56

<0.001

4.08

2.15–7.75

<0.001

2.34

1.49–3.68

<0.001

Distant metastases (M0 vs. M1)

—

—

—

6.77

3.94–11.6

<0.001

4.30

2.68–6.89

<0.001

Tumor location (Colon vs. Rectum)

1.46

0.78–2.74

0.236

0.93

0.54–1.60

0.791

0.91

0.57–1.44

0.679

Preoperative radiotherapy or chemoradiotherapy (No vs. Yes)

0.96

0.48–1.89

0.896

1.03

0.51–2.09

0.930

0.97

0.54–1.76

0.928

Normocytic anemia (No vs. Yes)

0.89

0.47–1.72

0.733

1.36

0.82–2.27

0.239

1.61

1.07–2.42

0.023

mGPS (0 vs. 1–2)

0.63

0.27–1.49

0.292

1.31

0.76–2.26

0.331

1.40

0.89–2.19

0.145

  1. The models aimed to enlighten the prognostic value of normocytic anemia in CRC, relative to TNM variables and systemic inflammation (mGPS). Abbreviations: CI: confidence interval; CSS: cancer specific survival; HR: hazard ratio; mGPS: modified Glasgow Prognostic Score; OS: overall survival; TTR: time to recurrence.
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