Table 1 Clinical data of patients analyzed in basophil activation test.

From: The high molecular weight dipeptidyl peptidase IV Pol d 3 is a major allergen of Polistes dominula venom

Patient ID

Skin test1 (i.c.) PDV

Skin test1 (i.c.) YJV

Skin test1 (i.c.) HBV

tIgE [kU/L]

sIgE PDV (i77) [kUA/L]

sIgE YJV (i3) [kUA/L]

sIgE HBV (i1) [kUA/L]

sIgE Pol d 5 (i210) [kUA/L]

sIgE Ves v 5 (i209) [kUA/L]

sIgE Ves v 1 (i211) [kUA/L]

sIgE Api m 1 (i208) [kUA/L]

1

neg.

0.001

neg.

55.5

n.d.

4.32

0.01

0.00

0.00

5.16

n.d.

2

1

1

neg.

237

15.3

10.6

0.02

36.1

23.5

0.07

0.00

3

0.1

0.1

neg.

12.3

1.07

0.35

0.02

0.85

0.27

0.17

0.00

4

n.d.

n.d.

n.d.

45.3

0.59

1.78

2.81

0.00

0.03

1.75

0.18

5

neg.

0.1

neg.

84

0.30

1.54

0.02

0.01

0.12

1.58

0.00

6

0.001

0.1

neg.

291

15.9

3.53

0.02

7.88

5.53

2.16

0.00

7

0.0001

0.1

neg.

305

35.6

20.0

0.10

14.4

2.07

24.1

0.00

8

0.01

0.1

0.1

168

4.34

3.55

1.16

1.9

1.21

3.93

0.35

9

0.1

0.01

neg.

53.5

1.98

2.11

0.02

1 2

1.2 2

n.d.

< 0.3 2

10

0.01

0.0001

neg.

313

42.3

22.4

0.16

17.5

9.76

22.8

0.02

11

n.d.

n.d.

n.d.

257

0.14

0.88

0.08

0.00

0.89

0.00

0.00

12

1

neg.

neg.

74.6

0.18

0.27

0.00

0.23

0.18

0.08

0.00

13

0.1

neg.

neg.

278

12.6

3.09

0.01

1.83

1.27

3.33

0.00

14

n.d.

0.01

neg.

22

n.d.

11.9

1.08

n.d.

12.1

0.00

0.00

15

n.d.

0.1

0.01

33.1

n.d.

0.79

0.58

n.d.

0.20

0.88

0.03

16

n.d.

0.01

0.0001

60

n.d.

1.45

16.2

n.d.

0.23

0.43

1.39

17

n.d.

0.0001

0.0001

91.6

n.d.

19.4

7.52

n.d.

1.82

12.7

0.31

18

n.d.

0.01

0.1

35.4

n.d.

0.46

0.73

n.d.

0.18

0.31

0.10

19

n.d.

0.001

0.1

202

n.d.

34.2

0.59

n.d.

34.2

7.90

0.22

20

n.d.

0.1

0.1

740

n.d.

3.26

1.48

n.d.

2.66

0.94

0.01

21

n.d.

0.001

0.0001

47

n.d.

0.94

15.7

n.d.

1.90

0.02

3.66

22

n.d.

neg.

0.001

21.7

n.d.

<0.1

6.60

n.d.

0.01

0.03

2.50

23

n.d.

0.001

neg.

197

n.d.

9.30

0.43

n.d.

6.72

4.71

0.02

24

n.d.

0.1

0.001

41.2

n.d.

1.61

12.6

n.d.

0.55

6.07

4.66

25

n.d.

0.01

0.1

181

n.d.

2.52

0.71

n.d.

7.80

0.06

0.06

26

n.d.

0.0001

neg.

68.6

n.d.

14.0

0.58

n.d.

7.56

0.08

0.01

27

n.d.

neg.

0.0001

568

n.d.

0.12

>100

n.d.

0.07

0.04

>100

28

n.d.

0.0001

0.0001

65.8

n.d.

1.29

3.29

n.d.

1.66

0.02

0.66

  1. Patients with a systemic reaction after an insect sting (grade I to IV according to Ring and Messmer46) were included for BAT. Patients 1 to 13 are from Spain (from the area of Barcelona) and allergic to PDV and/or YJV and patients 14 to 28 are from Germany (from the area of Munich) and allergic to YJV and/or HBV. sIgE and tIgE levels were determined using the UniCAP 250 system (Thermo Fisher Scientific). bold/italic: sIgE ≥ 0.35 kUA/L; bold: sIgE between 0.1 and 0.35 kUA/L.
  2. n.d., not determined; neg., negative.
  3. 1For intradermal skin tests the lowest venom concentration [µg/mL] that gave a positive result is displayed.
  4. 2Measured with ImmunoCAP-ISAC (Thermo Fisher Scientific).
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