Table 2 Hazard ratios and 95% confidence intervals for myocardial infarction, ischemic stroke, and death according to quartiles of liver enzymes.

ALT

Q1

48700

36870026

1.32

1.00 (ref.)

59161

36847085

1.61

1.00 (ref.)

179742

37046039

4.85

1.00 (ref.)

Q2

54532

35893859

1.52

1.00 (0.99, 1.01)

65599

35869654

1.83

1.00 (0.99, 1.01)

154118

36102372

4.27

0.89 (0.89, 0.90)

Q3

58359

34273199

1.70

1.02 (1.01, 1.03)

68356

34255343

2.00

1.02 (1.01, 1.03)

147344

34501798

4.27

0.91 (0.91, 0.92)

Q4

69993

37444966

1.87

1.10 (1.07, 1.10)

77226

37438130

2.06

1.06 (1.05, 1.07)

177221

37720098

4.70

1.17 (1.17, 1.18)

AST

Q1

40948

34854743

1.17

1.00 (ref.)

45806

34849351

1.31

1.00 (ref.)

110512

35011148

3.16

1.00 (ref.)

Q2

55205

38434636

1.44

0.97 (0.96, 0.98)

61766

38427855

1.61

0.95 (0.94, 0.96)

143560

38648886

3.71

0.91 (0.90, 0.92)

Q3

62827

37579639

1.67

0.97 (0.96, 0.98)

74750

37556028

1.99

0.96 (0.95, 0.97)

166036

37823728

4.39

0.95 (0.94, 0.95)

Q4

72604

33613032

2.16

1.05 (1.04, 1.06)

88020

33576979

2.62

1.04 (1.03, 1.05)

238317

33886545

7.03

1.30 (1.30, 1.31)

GGT

Q1

42421

36982585

1.15

1.00 (ref.)

48844

36974336

1.32

1.00 (ref.)

138441

37142806

3.73

1.00 (ref.)

Q2

51835

36735422

1.41

1.08 (1.06, 1.09)

59570

36723544

1.62

1.09 (1.08, 1.11)

143240

36934518

3.88

1.05 (1.04, 1.06)

Q3

60810

35233338

1.73

1.16 (1.15, 1.17)

70169

35217336

1.99

1.20 (1.18, 1.21)

153119

35470795

4.32

1.15 (1.14, 1.16)

Q4

76518

35530706

2.15

1.27 (1.26, 1.29)

91759

35494998

2.59

1.36 (1.34, 1.37)

223625

35822188

6.24

1.64 (1.63, 1.66)