Table 5 Levels of cytokines in serum in BChE K-carrier and no-carrier RR-MS patients and HD subjects.

From: Butyrylcholinesterase and Acetylcholinesterase polymorphisms in Multiple Sclerosis patients: implication in peripheral inflammation

BChE rs1803274

RR-MS

HD

ANOVA p-value

Carrier

No Carrier

Carrier

No Carrier

RR-MS vs HD

Carrier vs no carrier

Interaction

TNFα (pg/mL)

19.4 ± 2.1

16.9 ± 5.6

2.4 ± 0.9

4.8 ± 3.1

<0.001

0.065

0.564

IL-17 (pg/mL)

41.8 ± 13.9

40.4 ± 22.0

10.4 ± 5.2

16.8 ± 3.8

0.027

0.467

0.768

IL-18 (pg/mL)

357.0 ± 63.5

286.7 ± 41.8

168.2 ± 17.1

205.1 ± 22.0

<0.001

0.787

0.642

IL12/p40 (pg/mL)

329.3 ± 41.2

274.4 ± 15.9

76.7 ± 43.2

109.6 ± 36.9

<0.001

0.678

0.498

  1. Data are expressed as mean and standard deviation.