Table 8 Cytokines levels in AChE rs2571598 genotype carrier and no-carrier RR-MS patients and HD subjects.

From: Butyrylcholinesterase and Acetylcholinesterase polymorphisms in Multiple Sclerosis patients: implication in peripheral inflammation

AChE rs2571598

RR-MS

HD

ANOVA p-value

Carrier

No Carrier

Carrier

No Carrier

RR-MS vs HD

Carrier vs no carrier

Interaction

TNFα (pg/mL)

14.3 ± 3.6

16.9 ± 5.6

1.6 ± 1.2

4.8 ± 3.1

<0.001

0.051

0.617

IL-17 (pg/mL)

37.2 ± 18.2

40.4 ± 22.0

9.7 ± 4.8

16.8 ± 3.8

0.009

0.047

0.987

IL-18 (pg/mL)

283.6 ± 52.0

286.7 ± 41.8

168.9 ± 12.9

205.1 ± 22.0

<0.001

0.465

0.632

IL-12/p40(pg/mL)

276.4 ± 33.2

274.4 ± 15.9

80.4 ± 47.6

109.6 ± 36.9

<0.001

0.871

0.596

  1. Data are expressed as mean and standard deviation.