Table 1 2 × 2 contingency table for gene set enrichment test with QTL.

From: Statistical Approach for Gene Set Analysis with Trait Specific Quantitative Trait Loci

 

Overlapped with QTL regions

Not overlapped with QTL regions

Total

Selected gene set

N Gk Q

N Gk Q c

N Gk

Not selected gene set

N Gk c Q

N Gk c Q c

N Gk c

Total

N Q

N Q c

N

  1. Ω: gene space; N Gk : number of genes in Gk ; N Gk c: number of genes in Gk c; N Q : number of QTL hit genes in gene space: N Q c: number of non-QTL hit genes in gene space. Gk : k-th gene sample from selected gene set; Gk c: Ω- Gk .
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