Table 1 Comparison of baseline characteristics in patients vs. controls group.
From: MRI of the cervical spinal cord predicts respiratory dysfunction in ALS
Patients (n = 40) | Controls (n = 21) | p-value | |
---|---|---|---|
Characteristics | |||
Age | 56.18 (10.50) | 55.48 (13.43) | 0.82 |
Sex (men/women) | 33/7 | 15/6 | 0.34 |
Bilateral pre-central and central (motor) cortex | |||
Volume | 0.56 (0.08) | 0.67 (0.11) | <0.0001 |
R2 | 14.73 (1.54) | 15.17 (1.69) | 0.60 |
NAA | 1.41 (0.19) | 1.56 (0.18) | 0.005 |
Bilateral PLIC | |||
FA | 0.61 (0.05) | 0.62 (0.09) | 0.61 |
MD + , median [IQR] | 7.21 [7.03 ‒ 7.53] | 7.18 [6.75 ‒ 7.32] | 0.32 |
Medulla oblongata | |||
Volume | 0.20 (0.03) | 0.24 (0.04) | <0.0001 |
R2 | 16.85 (2.54) | 17.06 (2.44) | 0.76 |
FA | 0.33 (0.06) | 0.35 (0.14) | 0.56 |
MD + , median [IQR] | 8.31 [7.87 ‒ 9.50] | 9.02 [7.64 ‒ 13.64] | 0.50 |
Cervical spinal cord | |||
Volume, median [IQR] | 2437 [2117 ‒ 2736] | 2689 [2354 ‒ 2999] | 0.060 |
R2, median [IQR] | 38.13 [35.01 ‒ 46.13] | 37.60 [36.67 ‒ 40.44] | 0.71 |