Table 3 The skin irritant potential and cytotoxicity against HL-7702 cells of juglone and plumbagin.

From: Application of Sustainable Natural Resources in Agriculture: Acaricidal and Enzyme Inhibitory Activities of Naphthoquinones and Their Analogs against Psoroptes cuniculi

Group

Skin irritant potential (15 days)*

IC50 (µg/ml)

Healthy rabbits

Naturally infested rabbit

Control group

HL-7702 cell

Juglone

No irritation

No irritation

No irritation

>100

Plumbagin

No irritation

No irritation

No irritation

4

  1. *The grading standard for skin irritation or allergic response of ref.57 was adopted.
Back to article page