Figure 2 | Scientific Reports

Figure 2

From: Long range haplotyping of paired-homologous chromosomes by single-chromosome sequencing of a single cell

Figure 2

Whole-genome haplotyping. (a) The chromosomes from a single cell were diluted into eight tubes and sequenced. Each ring in the Circos plot represents data from one tube, and there were eight rings in total. The length of each line represents the mapped reads of each 1 million-bp window. Whether a chromosome was found in a tube was determined by the quantity of mapped reads. (b) Table that summarizes the chromosomes found in each tube. Eighteen pairs of homologous chromosomes were successfully separated. Chromosomes 11, 12, 15, 16, and 21, each was found in one tube or one copy was missing. The missing chromosomes may have been lost because of binding to the tube, or during transfer from the dish to the tube.

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