Figure 6
Synthesis of C13-methylene modified spiro[lactone-isoxazol] 1k–q. Conditions and reagents34: (a) 50% NH2OH in H2O, Et2O, 89%; (b) DMF, NCS, rt, 98%; (c) CH2Cl2, Et3N, rt, 26–96%.
Figure 6 | Scientific Reports
Synthesis of C13-methylene modified spiro[lactone-isoxazol] 1k–q. Conditions and reagents34: (a) 50% NH2OH in H2O, Et2O, 89%; (b) DMF, NCS, rt, 98%; (c) CH2Cl2, Et3N, rt, 26–96%.
