Table 1 1H (500 MHz) and 13C (125 MHz) NMR spectroscopic data for compound 1j and 1o (in CDCl3, δ in ppm).

From: Diversity Modification and Structure-Activity Relationships of Two Natural Products 1β-hydroxy Alantolactone and Ivangustin as Potent Cytotoxic Agents

Position

1j

1o

δH (J in Hz)

δC

δH (J in Hz)

δC

1

4.71 dd (11.7, 4.1)

81.9

 

212.5

2

1.96 m; 1.77 m

22.4

2.74 m; 2.24 m

35.5

3

1.71 m; 1.60 m (overlap)

29.2

1.99 m; 1.79 m

28.2

4

2.52 m (overlap)

38.1

2.70 m

36.6

5

 

152.2

 

149.9

6

5.23 d (3.1)

113.8

5.34 d (3.3)

116.2

7

3.01 m

43.6

3.08 m

43.0

8

4.99 m

76.6

5.18 m

76.4

9

2.34 m (overlap); 1.60 m (overlap)

38.9

2.53 dd (15.6); 1.90 dd (15.6)

33.8

10

 

37.8

 

47.2

11

 

87.2

 

89.5

12

 

173.1

 

173.1

13

2.34 m (overlap)

25.2

3.67 d (16.9); 3.48 d (16.9)

37.1

14

1.37 s

23.3

1.44 s

28.1

15

1.11 d (7.6)

22.9

1.30 d (7.3)

23.7

16

2.95 m; 2.52 m (overlap)

28.1

 

156.0

17

 

174.7

 

121.0

18

 

166.0

7.64 d (8.8)

128.6 (2C)

19

 

130.2

6.94 d (8.8)

114.3 (2C)

20

7.97 d (7.5)

129.6 (2C)

 

161.6

21

7.39 t (7.7)

128.5 (2C)

3.85 s (OCH3)

55.4 (OCH3)

22

7.51 t (7.4)

133.2

  
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