Figure 6 | Scientific Reports

Figure 6

From: Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells

Figure 6

Identified biosynthetic pathways of steroids in COS-7 cells. COS-7 cells express P450scc, 3β-HSDs, P4507α, P450c17, 17β-HSDs, 5α-reductases, P450c21, P450c11β, and P450arom. In addition, steroidogenic enzymes 3β-HSD, P4507α, 5α-reductase, P450c17, P450c21, P450c11β, and 17β-HSD were active in cultured COS-7 cells. Gray boxes indicate confirmed expression of mRNAs. White box indicates mRNAs that were not confirmed. Black arrows indicate confirmed activity of steroidogenic enzymes. White arrows indicate steroidogenic enzymes that were not confirmed.

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