Figure 8
From: Polygonum aviculare L. extract and quercetin attenuate contraction in airway smooth muscle
Mechanism of EAF- and quercetin-induced inhibition of TR precontraction. ACH or high levels of K+ induces precontractions in ASM by increasing intracellular Ca2+ via Ca2+-permeant ion channels. The channels are blocked by EAF and quercetin, resulting in a decrease in Ca2+, leading to ASM relaxation.
