Figure 7
Alcohol changes cytokine levels, depending on the dose. (A–J) Cytokine levels measured at the protein level in perfusion-desanguinated brain of mice chronically treated with alcohol, with the last dose of alcohol given on the same day as the experiment. CTR, saline; low, 0.5 g/kg ethanol; medium, 1.5 g/kg ethanol. IL, interleukin; IFNγ, interferon gamma; LIF, leukemia inhibitory factor; CCL 5, Chemokine C-C motif ligand 5. *p < 0.05, **p < 0.01, ***p < 0.001, one-way ANOVA with Tukey test. Mean and standard error of the mean (SEM) is indicated on the plots of individual values. 5, 10 and 11 mice per group for saline, low and medium alcohol groups, respectively. Some readings were out of range (not within the standard curve) and could therefore not be reported here.
