Table 1 Gradient profile for the liquid chromatographic separation samples collected from in vitro amide hydrolysis assays. For positive mode ESI mass spectrometric acquisitions, mobile phase A = 10 mM ammonium formate containing 0.1% (v/v) formic acid; mobile phase B = acetonitrile. For negative mode ESI mass spectrometric acquisitions, mobile phase A = 10 mM ammonium acetate; mobile phase B = acetonitrile.

From: Metabolic Hydrolysis of Aromatic Amides in Selected Rat, Minipig, and Human In Vitro Systems