Figure 3 | Scientific Reports

Figure 3

From: The role of disease-linked residue glutamine-913 in support of the structure and function of the human electrogenic sodium/bicarbonate cotransporter NBCe1-A

Figure 3

Effect of DIDS on currents mediated by WT or Q913X mutants in Xenopus oocytes. (A) Representative current-voltage (I–V) relationship from a H2O-injected oocyte as it was sequentially exposed to ‘Na (0 HCO3)’, ‘Na, HCO3’, and ‘Na, HCO3, +200 µM DIDS’ solutions. (B–H) Equivalent data from oocytes expressing WT, Q913R, Q913C, Q913E, Q913K, Q913L, or Q913S.

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