Figure 3
From: Quantitative Magnetization Transfer in Monitoring Glioblastoma (GBM) Response to Therapy
Summary histogram plots of qMT parameters for all patients in each cohort for (a,b) ROI type I and (c,d) ROI type II showing that between Day14 and Day0 the parameters increased for non-progressors but were relatively unchanged for progressors. Comparing the Day14 plots of amount of magnetization transfer (RM0b/Ra) for non-progressors between ROI type II and ROI type I shows that, there is an increase in the larger value portion (RM0b/Ra > 1.5) for ROI type II, which demonstrates the white matter entering the tumor area in non-progressors (RM0b/Ra has larger values for white matter compared to the tumor). The plots represent the mean and standard error of histogram probabilities of individual patients (histogram count normalized with respect to the number of voxels in the ROI) which are shown in supplementary material Figs S2 and S3.
