Table 2 Quantitative MT parameter values for progressors (P) and non-progressors (NP). Mean ± standard deviation across all subjects, derived from average parameter value over tumor ROI defined at each imaging time point (ROI type I).

From: Quantitative Magnetization Transfer in Monitoring Glioblastoma (GBM) Response to Therapy

Scan

 

\(R[{s}^{-1}]\)

\(R{M}_{0b}/{R}_{a}\)

\(1/({{\rm{R}}}_{{\rm{a}}}{{\rm{T}}}_{2{\rm{a}}})\)

\({T}_{2b}\,[\mu s]\)

\({R}_{{\rm{a}}}\,[{s}^{-1}]\)

\({M}_{0b}\,[ \% ]\)

Day0

NP

22.5 ± 5.0

1.06 ± 0.24**

16.2 ± 5.5*

12.1 ± 1.2

0.79 ± 0.20

5.0 ± 0.5

P

18.8 ± 3.5

1.64 ± 0.48

24.3 ± 8.8

11.6 ± 1.0

0.61 ± 0.15

6.6 ± 2.4

Day14

NP

19.3 ± 2.9

1.38 ± 0.39

22.7 ± 7.0

11.8 ± 1.1

0.63 ± 0.12

5.6 ± 1.6

P

20.5 ± 2.3

1.77 ± 0.50

25.3 ± 5.1

12.1 ± 1.8

0.58 ± 0.07

6.6 ± 3.1

Day28

NP

19.8 ± 4.9

1.43 ± 0.26

22.2 ± 5.9

11.8 ± 1.2

0.61 ± 0.10

5.6 ± 1.2

P

23.1 ± 8.4

1.71 ± 0.18

24.3 ± 3.4

11.0 ± 0.3

0.62 ± 0.17

5.8 ± 0.3

Day70

NP

22.0 ± 5.7

1.56 ± 0.40

24.1 ± 4.0

11.3 ± 1.5

0.56 ± 0.06

5.4 ± 1.4

P

19.1 ± 7.4

1.68 ± 0.06

26.0 ± 3.6

10.3 ± 1.1

0.57 ± 0.14

6.0 ± 1.1

  1. P: progressor, NP: non-progressor, *p < 0.05, **p < 0.01.