Table 2 Quantitative MT parameter values for progressors (P) and non-progressors (NP). Mean ± standard deviation across all subjects, derived from average parameter value over tumor ROI defined at each imaging time point (ROI type I).
From: Quantitative Magnetization Transfer in Monitoring Glioblastoma (GBM) Response to Therapy
Scan | \(R[{s}^{-1}]\) | \(R{M}_{0b}/{R}_{a}\) | \(1/({{\rm{R}}}_{{\rm{a}}}{{\rm{T}}}_{2{\rm{a}}})\) | \({T}_{2b}\,[\mu s]\) | \({R}_{{\rm{a}}}\,[{s}^{-1}]\) | \({M}_{0b}\,[ \% ]\) | |
---|---|---|---|---|---|---|---|
Day0 | NP | 22.5 ± 5.0 | 1.06 ± 0.24** | 16.2 ± 5.5* | 12.1 ± 1.2 | 0.79 ± 0.20 | 5.0 ± 0.5 |
P | 18.8 ± 3.5 | 1.64 ± 0.48 | 24.3 ± 8.8 | 11.6 ± 1.0 | 0.61 ± 0.15 | 6.6 ± 2.4 | |
Day14 | NP | 19.3 ± 2.9 | 1.38 ± 0.39 | 22.7 ± 7.0 | 11.8 ± 1.1 | 0.63 ± 0.12 | 5.6 ± 1.6 |
P | 20.5 ± 2.3 | 1.77 ± 0.50 | 25.3 ± 5.1 | 12.1 ± 1.8 | 0.58 ± 0.07 | 6.6 ± 3.1 | |
Day28 | NP | 19.8 ± 4.9 | 1.43 ± 0.26 | 22.2 ± 5.9 | 11.8 ± 1.2 | 0.61 ± 0.10 | 5.6 ± 1.2 |
P | 23.1 ± 8.4 | 1.71 ± 0.18 | 24.3 ± 3.4 | 11.0 ± 0.3 | 0.62 ± 0.17 | 5.8 ± 0.3 | |
Day70 | NP | 22.0 ± 5.7 | 1.56 ± 0.40 | 24.1 ± 4.0 | 11.3 ± 1.5 | 0.56 ± 0.06 | 5.4 ± 1.4 |
P | 19.1 ± 7.4 | 1.68 ± 0.06 | 26.0 ± 3.6 | 10.3 ± 1.1 | 0.57 ± 0.14 | 6.0 ± 1.1 |