Figure 2 | Scientific Reports

Figure 2

From: Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance

Figure 2

Primary transcriptome architecture of S. aureus USA300 TCH1516. (A) A total of 1,861 TSSs determined from four different experimental conditions were compared in condition-specific manner. (B) TSS (+1) was occupied with purine bases, while pyrimidine was enriched at −1 position. (C) Categorization of TSSs according to their relative position and direction to the downstream gene. TSSs positioned upstream (within 300 nt) of a gene with the same direction were annotated as primary (pTSS) or secondary (sTSS). TSSs located inside a gene without downstream gene in close vicinity (<300 nt) were annotated as internal (i) with the same direction of containing genes, or antisense (as) with the opposite direction against the containing genes. TSSs located intergenic region without cognate gene were annotated as orphan (o). (D) AgrBDCA operon was transcribed by a primary TSS and two secondary TSSs. Two Agr operator sites are located upstream of the primary TSS.

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