Figure 5

Quantification of lipid core in rabbit aortas in vivo. (a–c) Comparative result of quantitated lipid core depth (a), angle (b) and area of lipids (c) in a rabbit aorta (#3) at each frame along a pullback length of 60 mm with different rotational and pullback speeds (4 fps and 0.25 mm/s vs. 16 fps and 1 mm/s). Lipid core depth corresponds to the depth to catheter center where PA signal shows a maximum amplitude; angle of lipid core means the observation angle of the maximum lipid core from catheter center; area of lipids is obtained by counting all the lipids in and surrounding the arterial wall. (d–f) Average lipid core depth (d), angle (e), and volume of lipids in a 1 mm artery length (f) for two rabbit aortas (#2 and #3). The error bars are resulted from all the frames during entire pullbacks.