Figure 5
From: Integrating Functional Analysis in the Next-Generation Sequencing Diagnostic Pipeline of RASopathies
Structural assessment of cardiac tubes by in situ hybridization of cmlc1. Statistical significance was derived using a two-sided Fisher’s exact test to compare mutants with the corresponding WT. **p < 0.01; ns: not significant. (a) The proportion of zebrafish embryos with a normal or deformed heart tube structure. (b) Representative embryos with a normal and (c) deformed heart tube.
