Figure 5
RNAs enriched in CD63+ EVs. Analysis of specific classes of RNAs in the 271 differentially expressed non-coding RNAs that were enriched ≥ 2-fold in CD63+ EVs versus CD63- EVs were extracted from the scatter graph in Fig. 3b. A table was generated for each type of upregulated RNAs of captured CD63+ EVs. (a) Log2 total RPM values are plotted for the indicated snoRNAs from CD63+ EVs (blue bars) and uncaptured CD63- EVs. (b) Log2 total RPM values are plotted for the indicated tRNAs from CD63+ EVs (blue bars) and uncaptured CD63- EVs. (c) Log2 total RPM values are plotted for the indicated lncRNAs from CD63+ EVs (blue bars) and uncaptured CD63- EVs. (d) Log2 total RPM values are plotted for the indicated small nuclear RNAs from CD63+ EVs (blue bars) and uncaptured CD63- EVs. (e) Log2 total RPM values are plotted for the indicated ribosomal protein RNAs from CD63+ EVs (blue bars) and uncaptured CD63- EVs. Blue stars indicate RNAs that are also enriched in CD47+ or MHC1+ EVs. Red stars indicate RNAs enriched in all three types of captured EVs.
