Figure 6 | Scientific Reports

Figure 6

From: CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs

Figure 6

RNAs enriched in MHC1+ EVs. Analysis of specific classes of RNAs in the 268 differentially expressed non-coding RNAs that were enriched ≥ 2-fold in MHC1+ EVs versus MHC1− EVs were extracted from the scatter graph in Fig. 3c. A table was generated for each type of upregulated RNAs of captured MHC1+ EVs. (a) Log2 total RPM values are plotted for the indicated snoRNAs from MHC1+ EVs (blue bars) and uncaptured MHC1− EVs. (b) Log2 total RPM values are plotted for the indicated tRNAs from MHC1+ EVs (blue bars) and uncaptured MHC1− EVs. (c) Log2 total RPM values are plotted for the indicated lncRNAs from MHC1+ EVs (blue bars) and uncaptured MHC1− EVs. (d) Log2 total RPM values are plotted for the indicated small nuclear RNAs from MHC1+ EVs (blue bars) and uncaptured MHC1− EVs. (e) Log2 total RPM values are plotted for the indicated ribosomal protein RNAs from MHC1+ EVs (blue bars) and uncaptured MHC1− EVs. Blue stars indicate RNAs that are also enriched in CD63+ or MHC1+ EVs. Red stars indicate RNAs enriched in all three types of captured EVs.

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